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Magnetofection |
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New Transfection Technology
This method associates DNA with magnetic nanoparticles coated with
cationic molecules. The resulting molecular complexes are then
transported into cells supported by an appropriate magnetic field.
Magnetofection exploits magnetic force exerted upon gene vectors
towards, possibly even into, the target cells. In this manner, the
complete applied vector dose gets concentrated on the cells within a
few minutes so that 100% of the cells get in contact with a
significant vector dose. Inspired by the validated and recognised
magnetic drug targeting technology, this innovative method is a
revolution for transfection and infection.
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- Universal for all transfections, even hard to transfect cells
(adherent or suspension)
- Suitable for all nucleic acids (DNA, siRNA, mRNA, ODN and
viruses)
- Highly efficient transfections, even with low vector doses
- Simple and rapid protocol (mix, incubate and test)
- Only method to improve all transduction
- Exceptional with viruses particularly to increase infectivity or
infect non-permissive cells
- Non-toxic and economical
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Efficiency
Significantly increases transfection efficiency, even with very low
doses of DNA or vectors, by concentrating the genetic materials on the
cells.
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Transfection
PolyMag |
Increase transfection
CombiMag |
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Standard
PolyMag
Transfection
Magnetofection
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Reagent F alone
CombiMag+Reagent F |
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Confluent Primary Human Keratinocytes |
Confluent Primary Human Keratinocytes |
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Gene Silencing
SilenceMag |
Infection
ViroMag |
Control
SilenceMag
10nM siRNA
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Without magnetic field
With magnetic field |
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Stable GFP transfection of HeLa cells |
NIH 3T3 Cells lacking CAR receptor infected with an
Adenovirus (coding for LacZ +/- ViroMag |
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Versatility
OZ Biosciences offers four types of ready-to-use
reagents:
• PolyMag, designed for all nucleic acids
• SilenceMag, specific to siRNA delivery
• CombiMag, unique solution for all vectors: viruses
& transfection reagents
• ViroMag, unique solution for viral applications
Download manual for PolyMag
and CombiMag
Download manual for SilenceMag
Download manual for ViroMag
Download MSDS for
this product
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Do not
electroshock your cells anymore! |
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Non Toxic and Economic
• No expensive equipment required
• Save materials : very low doses of DNA are
sufficient
• Save money : less reagents are used
• Exceptional quality / price ratio
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| Order Code | Description | Size | Price | | FCM20100 | CombiMag | 100µl | £50.70 | | FCM20200 | CombiMag | 200µl | £89.60 | | FCM21000 | CombiMag | 1ml | £389.60 | | FMF10096 | Magnetic Plate | Each | £306.50 | | FKC30200 | Magnetofection Starting Kit (PN30100+CM20100+MF10000) | Each | £477.90 | | FKC30296 | Magnetofection Starting Kit (PN30100+CM20100+MF10096) | Each | £448.10 | | FKC30400 | Magnetofection Super Starting Kit (PN30100+SM10200+CM20100+MF10000) | Each | £555.80 | | FKC30496 | Magnetofection Super Starting Kit (PN30100+SM10200+CM20100+MF10096) | Each | £526.00 | | FPN31000 | PolyMag | 1ml | £828.60 | | FPN30100 | PolyMag | 100ul | £96.10 | | FPN30200 | PolyMag | 200pk | £180.50 | | FKM30200 | Selection Kit PN30100+CM20100 | Each | £146.80 | | FKM30350 | Selection Kit SiC CM20100+SM1020 | Each | £131.20 | | FKM30300 | Selection Kit SiP PN30100+SM10200 | Each | £175.30 | | FMF10000 | Super Magnetic Plate | Each | £336.40 | | FKM30400 | Super Selection Kit PN30100+CM20100+SM10200 | Each | £224.70 |
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